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![]() comments, ephemera, speculation, etc. (protected political speech and personal opinion) 2023- 2023-10-10 b THE STATE OF THE DISUNION IX READ THIS
ARTICLE ANYWAY.
*(I realize most of you did not take a Biochemistry class at Harvard College (like I did), however, a minimal science background is sufficient for you to understand the monstrous evil behind the fake pandemic, the unlawful "mandates" & the clot shots that did not prevent infection or transmission.) THERE CAN NOW BE NO DOUBT THAT THE SPIKE PROTEIN mRNA CLOT SHOTS WERE CREATED TO KILL. 5 ways
to skin a (genetically modified) cat
How many coincidences can there be in #plasmidgate? By now I sincerely hope that you have all been watching the exposure of the #PlasmidGate scandal unfold on twitter and various other platforms. If you haven’t I’m going to summarise it for you as briefly I can:
For more details on #Plasmidgate outside of twitter I would refer you to the original substack from Kevin McKernan here and the whole testimony of Dr Phillip Buckhaults here.
But this article is not directly about the discovery of Plasmid DNA in the Pfizer and Moderna jabs (that has been now verified by 6 labs worldwide). It’s about the special properties of the contents of that DNA and the RNA that is made from it, combined with the RNA that accompanies it (the jabs have the stated RNA in them as well as the stowaway DNA). You see, it turns out that there are at least 5 different mechanisms for that DNA-RNA-protein combination to take that DNA into the nucleus of your cells. And that wasn’t on the advertising brochure was it? Don’t believe me? See what Dr Phillip Buckhaults has to say about the Buckshot. I have clipped out the most important part from his speech to the SC Senate hearing and the most important bit of the most important bit is this:
Wait, what? They did something that increased the risk of genome modification? Now why would they do that, surely that’s an accident. And now we are here. Phillip quote’s Hanlon’s razor, viz: And I am going to show to you why the makers of the Pfizer and Moderna “mRNA vaccine” must be really, really, stupid if Hanlon’s Razor applies. It’s because in this one product there are at least 5 ways in which the product design and manufacture ended up with mechanisms that increase the risk of DNA going into the nucleus of your cells, thus modifying your genome. In other words, if they wanted to skin this particular cat, they managed to find 5 separate ways to do it and throw them into the same product. 1: The Lipid NanoparticlesI have addressed the LNPs previously in this article from last year which has attracted 23,000 reads to date…
Don’t take my word for it of course. Here is the Pfizer-BioNtech official document that tells you that the product transfects cells and that the LNP is more effective than the commercially available transfection kit (Ribojuice™, which is designed for RNA rather than DNA).In other words, those Lipid Nanoparticles are designed to get DNA into the nucleus of cells, and do that job with both DNA and RNA better than a commercially available transfection product. When I say that the LNP (which are cationic) are intended to deliver DNA into the nucleus this is not some random claim. It’s well known. Here from 2017:
What that means is that if the LNPs (or lipofectamine or any other cationic lipid particle) hang around for a few hours they will transfect (bring DNA into) the nucleus of any cell that it is in contact with. And in the case of
humans in which Yeah about that. The LNP exceeds the 4 hours easily in the ovaries, and remember that the study stopped recording this data at 48 hours even though they claimed that the animals were monitored for up to 9 days. ![]() (in response to https://x.com/arkmedic/status/1398803725272043520?s=20) And we knew that the distribution of LNPs to the ovaries was not only known about but was an intentional design back from a study in 2013 here. No “conspiracy theories” required. But I bet you didn’t see this mentioned in the consent form did you? Check the date on this tweet Now method one of skinning our cat is over, let’s move on to method two 2: Linearised plasmid DNASo, what on earth is that I hear you say? Let’s break it down:
Well DNA is what shouldn’t be in the product. It’s not RNA (which is the stuff that is meant to last for a few minutes and then get degraded, but that’s not what this article is about). It’s the nucleic acid type that makes up your genome, the stuff that is the blueprint for you. RNA is derived from DNA and makes the proteins that enable you to live. This is called the “Central Dogma of Molecular Biology” The bottom line being that, in general, if you want to have an effect on an organism (e.g. a person) using genetic methods, you can do this temporarily with RNA (which will then produce protein and should then degrade so it doesn’t produce any more) but if you want to make it more permanent you would use DNA and integrate it into the genome. Then when called on it will produce RNA which will produce protein. That process could happen for ever under the right circumstances. The step for RNA to produce protein usually happens immediately when RNA is produced (or introduced) in the cell. But for DNA to enact this process (to induce transcription and then translation) requires the DNA to have a signal to act. This is usually from a promoter which can respond to local signals and start the transcription process (it needs to be regulated so that it is not switched on all the time). There are multiple mechanisms for the regulations of RNA transcription and the elements that regulate (increase, decrease, start, stop) transcription don’t even need to be in the same area of the gene being regulated. It’s a complex process that we don’t know everything about for every gene. The point is that, if foreign DNA gets into your genome all hell can break loose - the most notable risk being cancer. This is because cancer is, in general, a situation where the control of cell growth and replication is disturbed. And cell growth and replication is a tightly controlled and complex system so any disturbance of it is either going to make cells grow more or less. Growing more cells without control is what gives you cancer. And this is known about in the field of gene therapy (where nucleic acid material is introduced to a person in order to correct a deficiency) such that one of the first gene therapies was stopped for this reason. This is “insertional oncogenesis” where cancer is caused by the insertion of additional fragments of DNA into areas of the DNA that interrupted the regulation mechanisms of that DNA. In fact all you need to create a cancer risk in a cell is for there to be enough “buckshot” (the term used by Phillip Buckhaults) for one of the pellets to stick itself where it doesn’t belong. And the more “buckshot” you have the higher the chance. When it comes to this particular buckshot we are talking about billions of copies of random DNA fragments. That’s a problem as discussed also here: And here And here So that is the “DNA” bit but what about the other bits - “Linearised Plasmid” Well, the plasmid is the circular loop of DNA that is used to transfect the E.Coli (the bacteria that make up the biggest constituent of poo). This is what a diagram of it looks like (actually, this is what Kevin McKernan found on sequencing because the original diagram from Pfizer had a lot of components hidden) This form of DNA is very good at getting into bacteria and getting them to produce what you need, which is the process that was used in “Process 2” of the Pfizer vaccine production. That is the one that was rolled out to the world - now designated #Poojabs because of the way it was produced. This was not explicitly declared to the public, by the way, and required the infamous freedom of information law suit to uncover as published by Josh Guetzkow here. However, plasmid
DNA is not normally that dangerous to humans because
it is readily destroyed by circulating enzymes. The
problem comes when the plasmid DNA is encapsulated
in a Lipid Nanoparticle. Then it doesn’t get
destroyed and whichever organism it gets injected to
may react in a similar way to the #poojabs bacteria
it was intended for. The mere presence of this
lab-tool in a medicinal product for which it was not
intended is therefore a regulatory no-no for this
and other reasons as outlined in the EMA guidelines here. Guideline Quality Non Clinical Clinical Aspects Gene Therapy Medicinal Products En So having lab-plasmid DNA intended for bacteria (which includes antibiotic resistance genes that you really don’t want injected into you) contaminating your “RNA therapy” is shocking enough, but what is Phillip saying about the small fragments? Well he says “little bitty lines” and that what he found was small fragments of DNA from the plasmid that they “tried to chop up” with enzymes. But it didn’t remove the lab-tool DNA at all, merely chopped it into little pieces. And do you know what happens when you chop a circular plasmid DNA into little pieces? It’s not circular anymore. It’s linear and that’s a problem. In fact it’s such a problem that this publication below shows that whatever they tried to do to the ends of linear DNA fragments they couldn’t stop them integrating into the genome with 10-20% of fragments (remember there are billions of them) integrating. You can see from the graphic that simply linearising the plasmid (red→ orange) significantly increases the amount of stable transfection (incorporation into the genome). So, that’s what Phillip and Kevin are talking about. Breaking the plasmid up into linear fragments doesn’t destroy it. It makes it more likely to integrate into the genome. If that was what you were trying to do, it would be a nice backup way to skin your cat. But we’re not finished yet… 3: The SV40 enhancerOne of the most shocking discoveries from Kevin McKernan’s sequencing analysis of the Pfizer vaccine was the inclusion of fragments of the SV40 promoter/enhancer. What’s that you ask? Well, SV40 is a monkey virus (Simian Virus hence SV) that is infamous for two things:
A gene enhancer is a switch that ramps up the production of gene product (protein) that it is affiliated with. In the case of SV40 the enhancer will essentially turn a gene on and never switch it off. The virus itself it has its own T-antigen protein that is produced in buckets due to the enhancer region, and this protein causes cells to divide in an uncontrolled fashion (hence cancer). The enhancer region therefore is popular for genomic scientists who want to get cells to produce proteins in large quantities, because it can be placed next to a gene of interest and it will be switched on permanently. Hence why it’s a lab tool.
The sequence map below shows that this wasn’t random with both versions containing the enhancer and… In the sequence map above you can see in the blue boxes (and pointed out by the authors) that there is one copy of a 72bp (base pair, or nucleotide pair) element in one version and two copies in another. This is 72bp element is directly from the SV40 genome and is seen in the enhancer of SV40 in either one of two copies . It’s not a random 72bp sequence.Therefore the inclusion of the SV40 enhancer region was deliberate and it should not have been anywhere near a product intended for human use. But remember this article is about one thing - elements of the vaccine properties that appear to increase the chance of DNA getting into the nucleus. The SV40 enhancer is dangerous because it can cause cancer or other problems if it gets into the human genome, but it has one other peculiar property. The SV40 enhancer region of the SV40 genome is a DNA nuclear targeting sequence (DTS or NTS) This is known from decades of work by David Dean of University of Rochester who was kind enough to discuss some of this with the Daily Beagle for their article here But to drive the point home, Dean showed conclusively that the 72bp sequence from that SV40 enhancer region was required in order to transport plasmid DNA (or any introduced DNA, for that matter) into the nucleus of cells (other than those undergoing cell division). So, not only did the people that made this product not seem to care whether there was a cancer-causing SV40 enhancer sequence injected into recipients, but that sequence was coincidentally the only one that could have been chosen that had a specific property of facilitating the transport of any foreign DNA that happened to be present into the nucleus. Cat skinning method number three complete, but the story is not over. 4. Spike protein nuclear localisation signalNow this one is much easier. Essentially, the spike protein (not the RNA or DNA) contains a special peptide sequence which acts as a nuclear transporter of any DNA that is attached to it. It’s one of many mechanisms for nuclear transport (that is, carriage of DNA into the nucleus) elucidated in this seminal review from the same David Dean here The common theme is that the DNA needs a nuclear localisation helper, which can be a Nuclear Localisation Signal (NLS, a specific sequence of amino acids in a protein in the cell) or a DNA transport sequence (DTS, discussed above in the SV40 section). By the way this only applies to cells that are not dividing. In cells that are dividing (undergoing mitosis) you don’t need any of these fancy mechanisms as shown in the graphic above - any free floating DNA will simply integrate. So, thankfully there are no proteins floating around with a Nuclear Localisation Sequence accompanying the Pfizer or Moderna (or Novavax) “vaccines”, right? Wrong. Here’s the paper. There are two interesting things about this massively important discovery.
Now I’ll need to take you back a little bit to December 2021. Remember this? That article paved the way for the publication of this paper confirming that the Furin Cleavage Site of the SARS-CoV-2 virus was derived from a Moderna patented gene sequence. In fact, Moderna have never got round to denying this - or that they had never created a working product and suddenly won the pharma lottery. Here’s the train wreck interview (archived). Now here’s the kicker. The Furin Cleavage Site, that was touted as the scary insertion that caused virulence of the scary virus - was kept in the vaccine sequence. That’s right. The highly toxic and inflammatory amino acid sequence QTNSPRRARSV, that was supposed to be one of the reasons for the “cytokine storm” (that was later found to be fake), was retained in the “vaccine” design. This is not normal in vaccine design and in fact the Spikogen vaccine removed this inflammatory fragment from its design, as it should. So, why would vaccine manufacturers (other than for Spikogen) keep this component in? Well, obviously it has nothing to do with the fact that the furin cleavage site contains this sequence: PRRARSV Which is exactly the same sequence as documented in the Sattar paper above and is a Nuclear Localisation sequence (NLS).
What a coincidence! Imagine incorporating something that the industry knew was dangerous into a RNA vaccine “not knowing” that this very thing would make any “contaminant” DNA get into the nucleus. How unlucky do these researchers have to be? [EDIT: The inimitable Jessica Rose reminded me about her substack from a year ago discussing the NLS and its location in the FCS here. Definitely worth revisiting if you have time] Well, planned or not, that gives us the fourth way that our genetically modified cat could be skinned. But four isn’t enough is it? I mean, if you really, really wanted to make sure that DNA could get integrated into the genome and you couldn’t guarantee that people would line up for repeated doses… You’d need a fifth option to guarantee that the product could integrate… 5. Open Reading Frame in the PolyA tailOK, I have to admit that now we’re in speculation territory. But there are just too many coincidences. The “PolyA tail” is the end cap on an mRNA sequence. It’s like the bottle cap on a bottle of fizzy pop. Without it, the pop will taste of something but it won’t have any fizz. The PolyA tail is a run of adenosines (AAAAAAA’s) added to the end of an RNA sequence and it serves to protect it from degradation as well as to allow export from the nucleus where it would be normally produced (from DNA) in a mammalian cell. Sounds fine, right? But, there is something not quite right with the PolyA tail in the Pfizer vaccine sequence, and no explanation for it that I have been able to find. Here it is
And what is weird about it is that the middle bit GCATATGACT has a sequence that contains a “start codon”, that is a triplet that tells the ribosome to start translating from RNA to a protein. There is no logic for it to be there. Now we can put this sequence into a protein translator program and get this: The tool tells us what will translate (in pink) and which requires a “M” (Methionine) to start any protein. The code for “M” here is ATG which is in that polyA tail sequence (but shouldn’t be).
Of course, that couldn’t happen because “stop codon read through” - where the normal signals to stop translating a protein when a “stop codon” is encountered is ignored and translation keeps going - can’t happen can it? And it certainly couldn’t translate the polyA tail in the “untranslated region (UTR)” could it? Well, it could under certain circumstances. One of those circumstances would occur if, instead of using standard RNA (containing uracil), the designers used “pseudouridine” (a synthetic version of uracil). Which is precisely what happened in the case of the Pfizer and Moderna “mRNA vaccines”. Pseudouridine is known to carry a risk of precisely this event happening. And, again totally coincidentally, Pfizer and Moderna presumably knew about this problem because instead of just one stop codon (the termination code for RNA translation) in the RNA sequence, Pfizer had two and Moderna had three. Which is like putting an extra set of brakes on your car because you knew that the first set would fail. The very existence of these at least allows us to drop one of our favourite geeky memes SummaryI’ve come to the
end of this little trip around the “mRNA” COVID
vaccine sequences and their Fortunately they thought about all this when they rolled out the therapy and they also thought about the impact in gametes (sperm and egg cells) which would pass on that signal to the next generation. And on that note I will leave you with an excellent graphic from an anoymous(e) twitter account which should give you an idea of the scale of the problem that we could be dealing with in terms of heritability of these DNA fragments. Fortunately we are protected by our drug regulators, who knew all this when they approved these drugs. They did, didn’t they? [There is a short update to this article here] 1
The terms used in this and linked article will be context dependent. A “transfection agent”, “transfectant agent” or “transfection reagent” is the product that is used to help transfect cells. The resulting cells are transfectants (or transfected cells). 2
TGA FOI 2389 document 6 (reduced redaction version) 3 Herr, W. The SV40 enhancer: transcriptional regulation through a hierarchy of combinatorial interactions. Seminars in Virology (4) 1993:3-13. The genomic
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